The mixing, separation, and reactions of fluids in the microscale offer numerous advantages. The flows are laminar and form highly stable phase boundaries. These benefits are leveraged in various microscale applications, including fuel cells, inkjet printers, 3D printers, the food industry, personal care products, lab-on-a-chip technology, and more. Insulin pumps for diabetics are a typical example. The challenges for digital twins in the microscale involve the accurate mathematical treatment of low physical diffusions. IANUS is a leader in algorithmic solutions for complex geometries, rheologies, and low diffusions!